This Cheddar-Stuffed Meatloaf is a tasty twist on a classic dish. It features a juicy meatloaf filled with gooey, melted cheddar cheese that brings a cheesy goodness to every bite.
I love how this meatloaf is not only hearty but has a fun surprise in the middle! It’s perfect for family dinners, and who can resist that cheesy center? Yum! 🍽️
Key Ingredients & Substitutions
Ground Beef: You can use a mix of beef and pork for a bit more flavor or even turkey for a leaner option. Just keep in mind that the fat content affects the meatloaf’s moisture.
Breadcrumbs: I like using plain breadcrumbs, but you can swap in crushed crackers or even oatmeal if you need a gluten-free option. Just make sure to adjust the liquid slightly as needed.
Cheddar Cheese: Sharp cheddar works best for a strong flavor. If you want something milder, go for regular cheddar or even try Monterey Jack or Pepper Jack for a little heat!
Ketchup: You can use BBQ sauce or even a homemade tomato sauce if you prefer. This changes the flavor profile, but it can be a fun twist!
What’s the Best Way to Keep Meatloaf Moist?
Keeping your meatloaf juicy can be tricky! Here are some tips:
- Don’t skip the milk and egg—they’re key to moisture and binding.
- Avoid overmixing the meat! Just mix until ingredients are combined.
- Let the meatloaf rest after baking. This helps redistribute the juices.
Following these steps ensures you’ll have a delicious and moist meatloaf that everyone will love!

Cheddar-Stuffed Meatloaf
Ingredients:
- 1 ½ pounds ground beef (or a mix of beef and pork)
- 1 cup breadcrumbs
- 1 small onion, finely chopped
- 2 cloves garlic, minced
- 1 large egg
- ¾ cup milk
- 1 tablespoon Worcestershire sauce
- 1 teaspoon dried oregano
- 1 teaspoon dried basil
- Salt and black pepper to taste
- 1 to 1 ½ cups shredded sharp cheddar cheese
- ½ cup ketchup (for topping)
- 1 tablespoon brown sugar (optional, for topping)
- Fresh parsley, chopped (for garnish)
Time Estimate:
This delicious cheddar-stuffed meatloaf will take about 15 minutes to prepare and around 60 to 75 minutes to cook. Add an extra 10 minutes to allow it to rest before slicing. In total, you’re looking at about 1 hour and 40 minutes from start to finish!
Instructions:
1. Preheat the Oven:
Start by preheating your oven to 350°F (175°C). This ensures it’s hot enough for a perfectly cooked meatloaf.
2. Mix the Ingredients:
In a large mixing bowl, combine the ground beef, breadcrumbs, finely chopped onion, minced garlic, egg, milk, Worcestershire sauce, oregano, basil, salt, and pepper. Mix everything together until it’s well combined. Be careful not to overmix, as this can make the meatloaf tough.
3. Form the Meatloaf:
Take half of the meat mixture and shape it into a loaf on a lined baking tray or place it in a lightly greased loaf pan, creating a nice even shape.
4. Add the Cheese:
Sprinkle the shredded cheddar cheese over the center of the meat mixture, making sure to leave about a ½-inch border around the edges to keep the cheese from spilling out.
5. Seal the Cheese:
Carefully cover the cheese with the remaining meat mixture, pressing gently to seal the cheese inside. This will create that delicious melty surprise when you slice it.
6. Add the Topping:
In a small bowl, mix together the ketchup and brown sugar (if using) and spread it evenly over the top of the meatloaf. This gives it a nice tangy flavor and sweetness!
7. Bake the Meatloaf:
Place the meatloaf in your preheated oven and bake for about 60 to 75 minutes, or until it reaches an internal temperature of 160°F (71°C).
8. Add Extra Cheese (Optional):
If you want a cheesier topping, about 10 minutes before the meatloaf is done, sprinkle some extra shredded cheddar on top and continue baking until melted and bubbly.
9. Let It Rest:
Once baked, remove the meatloaf from the oven and let it rest for about 10 minutes. This helps keep the juices locked in and makes slicing easier.
10. Serve:
Garnish with freshly chopped parsley and serve with your favorite sides like mashed potatoes, veggies, or a simple salad. Enjoy your delicious cheddar-stuffed meatloaf—each slice reveals that wonderful melted cheese surprise inside!
Can I Use Ground Turkey Instead of Beef?
Absolutely! Ground turkey is a great lean alternative. Just keep in mind that turkey may result in a drier meatloaf, so adding a bit more milk or an extra egg can help maintain moisture.
How Do I Store Leftover Meatloaf?
Store any leftover meatloaf in an airtight container in the fridge for up to 3 days. You can also wrap it tightly in aluminum foil or plastic wrap. To reheat, warm it in the oven at 350°F (175°C) until heated through.
Can I Add Vegetables to the Meatloaf Mix?
Yes, you can! Finely chopped bell peppers, carrots, or mushrooms can be added for extra flavor and nutrition. Just make sure to sauté them first to reduce moisture content.
What Can I Use If I Don’t Have Breadcrumbs?
If you’re out of breadcrumbs, you can substitute with crushed crackers, cooked rice, or even oatmeal. Just adjust the liquid in the recipe accordingly to maintain the right consistency.
